Making it personal – population health management and the NHS

Making it personal: translational bioinformatics

One of the most exciting research areas in Translational Bioinformatics 2 is related to the redefinition of fundamental notions of what constitutes a ‘disease.’ Nosology, the systematic classification of diseases, dates back to Carl Linnaeus, with the Genera Morborum Today, the improvement in our abilities to make molecular measurements related to health and disease has largely driven the revol...

Making it personal; mentoring future family docs.

Biomarkers for rheumatoid arthritis: making it personal.

Effective treatment of rheumatoid arthritis (RA) has been hampered by the heterogeneity of the disease. Although early intervention can result in disease remission, it requires early diagnosis - and current diagnostic tests are not sufficiently accurate or sensitive in the early stages of RA. As a result, RA is typically diagnosed only once damage to the joints has already begun, a time at whic...

Evidence-based management in the NHS: is it possible?

The rise of evidence-based medicine and more recently evidence-based policy reflect the increasing importance of evidence as a basis for the organisation and delivery of health care. Evidence-based practice is central to the "modernisation" of health care in current UK policy. The latest manifestation of this process is the emergence of evidence-based management in health care. This paper exami...

Translating Health IT Policy into Practice in the UK NHS

The challenge to provide a nation-wide integrated health service is central to UK government policy. The National Program for Information Technology was launched in 2002 to transform healthcare using information and communications technology. As the largest, non-military, non-scientific government funded IT program worldwide, it was planned over a decade with an estimated total cost expected to...